Comparative Evaluation of Coronally Advanced Flap Procedure in Conjunction with Amniotic Membrane Versus Coronally Advanced Flap with Platelet-Rich Fibrin Membrane in Patients with Miller's Class I and II Gingival Recession Defects
Citation Information :
Lamba S, Dahiya R, Blaggana A, Gulia K, Phogat A, Sharma J. Comparative Evaluation of Coronally Advanced Flap Procedure in Conjunction with Amniotic Membrane Versus Coronally Advanced Flap with Platelet-Rich Fibrin Membrane in Patients with Miller's Class I and II Gingival Recession Defects. 2022; 10 (2):70-76.
Introduction Amnion membrane (AM) and platelet-rich fibrin (PRF) have been used as Guided Tissue Regeneration (GTR)-based root coverage procedures in treatment of gingival recession. The objective of the present study was to comparatively evaluate the coronally advanced flap (CAF) procedure in conjunction with AM versus CAF with PRF in patients with Miller's class I and II gingival recession defects (GRD).
Materials and Methods The sample size (Miller's Class I and Class II GRD) consisted of 24 patients who were stratified into two groups randomly (12 for each group). Group A patients were treated by CAF with PRF and Group B patients were treated by CAF with AM. Clinical parameters comprising plaque index (PI), gingival index (GI), pocket probing depth (PPD), clinical attachment level (CAL), and GRD were assessed at baseline, 3 months, and 6 months postoperatively.
Results The percentage of root coverage obtained in the study groups was 62% and 77%, respectively, for Groups A and B. Statistically significant difference was obtained in the clinical parameters (PPD, CAL, and GRD) of Group B, which was treated by CAF with AM.
Conclusion Significant difference was found between Group A (CAF+ PRF) and Group B (CAF+ AM) membrane treated sites in reduction of PPD, gain in clinical attachment level, reduction of GRD from baseline to 3 months and baseline to 6 months, with more significant results seen with Group B.
Healing of bone defects by guided tissue regeneration. Plast Reconstr Surg 1988;81(05): 672–676
Use of platelet-rich fibrin membrane following treatment of gingival recession: a randomized clinical trial. Int J Periodontics Restorative Dent 2012;32(02): e41–e50
An opportunity in perioimplantology: The PRF. Implantodontie 200142:55–62
Platelet concentrates. Part 2: Associated biology. Implantodontie 2003;12:17–25
Trends over 30 years, 1973- 2003, in the prevalence and severity of periodontal disease. J Clin Periodontol 2008;35(05):405–414
Periodontal conditions in Swiss army recruits: a comparative study between the years 1985, 1996 and 2006. J Clin Periodontol 2007;34(10):860–866
Treatment of gingival recession with coronally advanced flap procedures: a systematic review. J Clin Periodontol 2008;35(8, Suppl)136–162
Root coverage esthetic score: a system to evaluate the esthetic outcome of the treatment of gingival recession through evaluation of clinical cases. J Periodontol 2009;80(04):705–710
Evaluation of the safety and efficacy of periodontal applications of a living tissue-engineered human fibroblast-derived dermal substitute. II. Comparison to the subepithelial connective tissue graft: a randomized controlled feasibility study. J Periodontol 2005;76(06):881–889
Coronal positioning of existing gingiva: short term results in the treatment of shallow marginal tissue recession. J Periodontol 1989;60(06):316–319
Development and clinical evaluation of a root coverage procedure using a collagen barrier membrane. J Periodontol 1997;68(08):770–778
Coronally advanced flap with or without enamel matrix derivative for root coverage: a 2-year study. J Clin Periodontol 2005;32(11):1181–1187
Clinical evaluation and comparison of the efficacy of coronally advanced flap alone and in combinationwith platelet rich fibrin membrane in the treatment of Miller Class I and II gingival recessions. Contemp Clin Dent 2015;6(02):153–160
Comparison of coronally advanced and semilunar coronally repositioned flap for the treatment of gingival recession. J Clin Diagn Res 2014;8(06): ZC04–ZC08
Root coverage grafting comparing placental derived membrane to acellular dermis matrix: a case series. Dentistry 2012;2(5):1–4
Comparative evaluation of coronally advanced flap using amniotic membrane and platelet-rich fibrin membrane in gingival recession: an 18-month clinical study. Contemp Clin Dent 2018;9(02): 188–194
Bilateral multiple recession coverage with platelet-rich fibrin in comparison with amniotic membrane. J Indian Soc Periodontol 2014;18(01):102–106
Root coverage using acellular dermal matrix and comparing a coronally positioned tunnel with and without platelet-rich plasma: a pilot study in humans. J Periodontol 2009;80(03):397–404
Comparative clinical evaluation of coronally advanced flap with or without platelet rich fibrin membrane in the treatment of isolated gingival recession. J Indian Soc Periodontol 2015; 19(01):66–71
Clinical evaluation of a modified coronally advanced flap alone or in combination with a platelet-rich fibrin membrane for the treatment of adjacent multiple gingival recessions: a 6-month study. J Periodontol 2009;80(02):244–252
A split mouth randomized controlled study to evaluate the adjunctive effect of platelet-rich fibrin to coronally advanced flap in Miller's class-I and II recession defects. J Indian Soc Periodontol 2013;17(05):631–636
Platelet rich fibrin: a promising approach for root coverage. J Interdiscip Dent 2011; 1:115–118
A novel dehydrated amnion allograft for use in the treatment of gingival recession: a case report. Journal of Research and Advancement 2014;3:176–181
A novel dehydrated amnion allograft for use in the treatment of gingival recession: an observational case series. Journal of Implant and Advanced Clinical Dentistry 2009;1:42–56
Amnionmembrane for coverage of gingival recession: a novel application. Contemp Clin Dent 2014;5 (03):293–295
