Citation Information :
Makkar S, Javed I, Thakur R, Negi S, Aggarwal V, Awasthi A. Efficacy of Cryotreated NaOCl on Soft Tissue Dissolution: An In Vitro Study. 2023; 11 (2):62-65.
Objective: The most frequent endodontic irrigant is sodium hypochlorite due to its antibacterial and tissue-dissolving properties. Recently, in endodontics, cryotherapy has been suggested to be an effective technique for controlling postoperative pain. The purpose of the study was to assess the effectiveness of cryotreated NaOCl for tissue dissolution.
Materials and methods: Palatal mucosal tissue of goat was collected to determine a benchmark of tissue dissolution properties of NaOCl at different temperatures. Fifteen pieces of palatal mucosa of goat of similar size were prepared and weighed. The sample was then randomly divided into three experimental groups, depending on the temperature of 5.25% NaOCl irrigant. Group I—tissue treated with warm 5.25% NaOCl, Group II—tissue treated with 5.25% normal NaOCl, Group III—tissue treated with 5.25% cryotreated NaOCl. Following an approximate exposure period of 2 minutes, the remaining tissue samples were taken out, blot dried, and checked for their weight gain. The variation in the weight of tissue in the pre-dissolution period and post-dissolution period was noted as residual weight.
Results: Kruskal–Wallis test showed that the time taken for complete dissolution was statistically significantly different among different groups (p < 0.001), with a mean rank tissue dissolution readings of 3.50 for warm NaoCl, 9.50 for normal NaOCl and 15.50 for cryotreated NaOCl.
Conclusion: Tissue dissolution with cryotreated NaOCl was less compared with normal and warm NaOCl. Cryotreated NaOCl did dissolve the tissue, but dissolution was slower when compared with normal and warm NaOCl.
Key message: To evaluate the efficacy of cryotreated NaOcl on soft tissue.
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