Introduction: The determination of a tooth-size to arch length discrepancy in mixed dentition requires an accurate prediction of the mesiodistal width of the unerupted permanent teeth. The Moyers mixed dentition space analysis is the non-radiographic method for detecting tooth-size arch length discrepancies. Moyers analysis was developed for North American children. Anthropological studies reveal that tooth size varies among different races and ethnicities. Aim: The present study was aimed to determine the applicability of Moyers mixed dentition arch analysis in children of Baddi, Himachal Pradesh. Materials and methods: Dental study models of 120 children in age group of 13- 16 years, were analysed who presented with complete eruption of permanent mandibular incisors, maxillary and mandibular canines & premolars. All dentitions were required to be free of any signs of dental pathology or anomalies. Measurements of the mesiodistal dimensions of the mandibular and maxillary teeth were made using a digital caliper with a Vernier scale that was calibrated to the nearest 0.01mm. The values were then subjected to statistical analysis. Results: All tooth groups showed highly significant differences (p<0.001) between mesiodistal widths in male and female subjects. Significant differences (p<0.05) were found between actual widths and the Moyers tables at almost all percentile levels, including the recommended 75%. Conclusion: The differences noted between predicted values from the Moyers tables and that of the present investigation might be the result of racial and ethnic diversity.