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VOLUME 9 , ISSUE 3 ( September-December, 2021 ) > List of Articles

Original Article

Evaluation of the Efficacy of Coenzyme Q10 in the Management of Chronic Periodontitis: A Clinical Study

Gaurav Pandav, Sakshi Pandav, Sanjeev Jain, Divya Saxena, Ridhi Aggarwal, Prerna Gulati

Keywords : antioxidants, chronic periodontitis, coenzyme Q10

Citation Information : Pandav G, Pandav S, Jain S, Saxena D, Aggarwal R, Gulati P. Evaluation of the Efficacy of Coenzyme Q10 in the Management of Chronic Periodontitis: A Clinical Study. 2021; 9 (3):138-146.

DOI: 10.1055/s-0041-1736267

License: CC BY-NC-ND 4.0

Published Online: 18-10-2021

Copyright Statement:  © 2021. Bhojia Dental College and Hospital affiliated to Himachal Pradesh University.


Abstract

Aim The present study was aimed to clinically evaluate the effectiveness of coenzyme Q10 (CoQ10) in the management of chronic periodontitis. Materials and Methods A total of 60 patients aged between 30 and 60 years with bleeding on probing and probing pocket depth (PPD) of 3 to 5 mm were selected and divided into three groups, with group I receiving scaling and root planing, group II CoQ10 formulation for 6 weeks, and group III receiving both scaling and root planning, followed by coenzyme Q10 administration for 6 weeks. PPD, relative attachment level (RAL), and gingival index were recorded in all the groups at baseline, 6 weeks, and 3 months, respectively. The data was statistically analyzed using Kruskal–Wallis, Mann–Whitney, and Wilcoxon signed rank tests. Result Intragroup comparison showed statistically significant difference (p ≤ 0.05) between the clinical parameters of all the groups at all time intervals, whereas intergroup comparison of all the parameters showed high statistically significant difference (p ≤ 0.001) in group III at various time intervals followed by group I and group II. Conclusion It was concluded from the study that CoQ10 is a useful adjunct in treating chronic periodontitis by boosting the host resistance to periodontal disease.

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