Citation Information :
Garima, Jain M, Deol S, Sharma M, Ahuja G. The Effect of Etiology on the Function of Hertwig's Epithelial Root Sheath in Regenerative Endodontic Procedures—A Review of Literature. 2022; 10 (3):111-114.
The management of nonvital immature permanent teeth poses quite a challenge. The apexification procedure is in use for long-term now but the treated teeth are more prone to fracture questioning the long-term prognosis of this technique. The introduction of regenerative procedures for the treatment of these teeth is quite favorable; however, despite the increasing use of regenerative endodontic therapy procedures, inconsistent results are seen in the root development. Conservation of Hertwig's epithelial root sheath may have a prime role and selecting the cases with viable root sheath may impact on the consistent positive results treated with regenerative procedures. This article aims to look at the database to find the role of etiology and its implication on Hertwig's epithelial root sheath in the outcome of regenerative endodontics.
Comparison of mineral trioxide aggregate and calcium hydroxide for apexification of immature permanent teeth: a systematic review and meta-analysis. J Formos Med Assoc 2016;115(07):523–530
Hertwig's epithelial root sheath: a panoramic view. Int J Appl Dental Sci 2017;3(04):21–25
Cellular andmolecular mechanisms of tooth root development. Development 2017;144(03):374–384
Development of immortalized Hertwig's epithelial root sheath cell lines for cementum and dentin regeneration. Stem Cell Res Ther 2019;10 (01):3
Does the etiology of pulp necrosis affect regenerative endodontic treatment outcomes? A systematic review and meta-analyses. J Evid Based Dent Pract 2020;20(01): 101400
Traumatized immature teeth treated with 2 protocols of pulp revascularization. J Endod 2014;40(05):606–612
Regenerative endodontic procedures for traumatized immature permanent teeth with severe external root resorption and root perforation. J Endod 2020;46(11):1610–1615
Treatment of necrotic teeth by apical revascularization: meta-analysis. Sci Rep 2017;7(01):13941
Drawbacks and unfavorable outcomes of regenerative endodontic treatments of necrotic immature teeth: a literature review and report of a case. J Endod 2012;38(10):1428–1434
Regenerative endodontic treatment with orthodontic treatment in a tooth with dens evaginatus: a case report with a 4-year follow-up. J Endod 2018;44(06): 952–955
Regenerative endodontic treatment of an immature permanent tooth at an early stage of root development: a case report. J Endod 2013;39 (05):719–722
Regenerative endodontics versus apexification in immature permanent teeth with apical periodontitis: a prospective randomized controlled study. J Endod 2017;43 (11):1821–1827
Clinical and radiographic outcomes of traumatized immature permanent necrotic teeth after revascularization/revitalization therapy. J Endod 2014;40(12):1946–1952
Dens evaginatus: a problem-based approach. Case Rep Dent 2015;2015:393209
Dens evaginatus on maxillary first premolar: report of a rare clinical case. J Nat Sci Biol Med 2012;3 (02):192–194
Regenerative endodontic treatment (revascularization) for necrotic immature permanent molars: a review and report of two cases with a new biomaterial. J Endod 2011;37(04):562–567
Revascularization in immature permanent teeth with necrotic pulp and apical pathology: case series. Case Rep Dent 2017;2017:3540159
Use of platelet-rich plasma for regeneration in non-vital immature permanent teeth: clinical and cone-beam computed tomography evaluation. J Int Med Res 2017;45(02):583–593
Treatment outcomes of apexification or revascularization in nonvital immature permanent teeth: a retrospective study. J Endod 2017;43(02):238–245
